PentaGen
FISH probes
FISH probes
FastProbe probes (CE IVD)
HealthCare Biotechnology produces FISH probes for pathology and hemato-oncology, with the main advantage of reduced hybridization time. The probes target non-repetitive sequences, resulting in increased specificity and reduced background signal.
| Breast tumors | HER2/CEP17 |
| TOP2A/CEP17 | |
| MYC/CEP8 | |
| Lung tumors | ALK |
| ROS1 Break appart | |
| C-MET/CEP7 | |
| Bladder tumors | CEP3/CEP3 |
| p16 | |
| p53 | |
| Brain tumors | BRAF |
| C11orf-95/RELA | |
| Aplastic anemia | D7S486/CEP7 |
| D20S108/20q13.12 | |
| CCND1/CEP11 | |
| CEP8 | |
| EGR1 del | |
| BCL1 Break apart | |
| ALL | TEL/AML1 |
| IGH Break appart | |
| P16/CEP9 | |
| CEP4/CEP10 | |
| MYC Break apart | |
| BCR/ABL | |
| CDK2NA/CEP9 | |
| KMT2A (MLL) Break apart | |
| CEP17 | |
| Cervical tumors | TER/CEP3 |
| C-MYC/CEP8 | |
| CLL | D13S319/LAMP1 |
| p53/CEP17 | |
| CEP11/ATM | |
| RB1/ATM | |
| CEP12 | |
| MYB/CEP6 | |
| Lymphomas | BCL6 Break appart |
| IGH Break appart | |
| BCL2/IGH | |
| MYC gene break | |
| BCL2 Break appart | |
| C-MYC/IGH | |
| P53 | |
| CCND1 (BCL1)/IGH | |
| CML | BCL2/IGH |
| BCR/ABL | |
| p53/CEP17 | |
| ASS1/CEP9 | |
| AML | AML1/ETO |
| CBFB | |
| CBFB/MYH11 | |
| PML/RARA | |
| MLL | |
| Multiple myeloma | 1q21 |
| p53/CEP17 | |
| D13S319/LAMP1 | |
| RB | |
| IGH | |
| MDS | EGR1/D5S630 |
| D7S486/CEP7 | |
| D20S108/CEP8 | |
| 7q22.1-22.2/q31.2 | |
| CSF1R/D5S630 | |
| D7S522/CEP7 | |
| CEPY/CEPX | |
| 20q12/20q13.12 |
A complete list of probes is available on request (info@pentagen.hu or diagnostika@pentagen.cz)
