PentaGen

FISH probes

FISH probes

FastProbe probes (CE IVD)

HealthCare Biotechnology produces FISH probes for pathology and hemato-oncology, with the main advantage of reduced hybridization time. The probes target non-repetitive sequences, resulting in increased specificity and reduced background signal.

Breast tumors HER2/CEP17
  TOP2A/CEP17
  MYC/CEP8
   
Lung tumors ALK
  ROS1 Break appart
  C-MET/CEP7 
   
Bladder tumors CEP3/CEP3
  p16
  p53
   
Brain tumors BRAF
  C11orf-95/RELA
   
Aplastic anemia D7S486/CEP7
  D20S108/20q13.12
  CCND1/CEP11
  CEP8
  EGR1 del
  BCL1 Break apart
   
ALL TEL/AML1
  IGH Break appart
  P16/CEP9
  CEP4/CEP10
  MYC Break apart
  BCR/ABL
  CDK2NA/CEP9
  KMT2A (MLL) Break apart
  CEP17
   
Cervical tumors   TER/CEP3
  C-MYC/CEP8
   
CLL D13S319/LAMP1
  p53/CEP17
  CEP11/ATM
  RB1/ATM
  CEP12
  MYB/CEP6
   
Lymphomas BCL6 Break appart
  IGH Break appart
  BCL2/IGH
  MYC gene break
  BCL2 Break appart
  C-MYC/IGH
  P53
  CCND1 (BCL1)/IGH
   
CML BCL2/IGH
  BCR/ABL
  p53/CEP17
  ASS1/CEP9
   
AML AML1/ETO
  CBFB
  CBFB/MYH11
  PML/RARA 
  MLL
   
Multiple myeloma 1q21
  p53/CEP17
  D13S319/LAMP1
  RB
  IGH
   
MDS EGR1/D5S630
  D7S486/CEP7
  D20S108/CEP8
  7q22.1-22.2/q31.2
  CSF1R/D5S630
  D7S522/CEP7
  CEPY/CEPX
  20q12/20q13.12

 

A complete list of probes is available on request (info@pentagen.hu or diagnostika@pentagen.cz)

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