Archer TMB panels

NGS panels for detection of somatic mutations and other genetic biomarkers (incl. TMB, MSI) for comprehensive genomic profiling of solid tumors.

More detailed product information

VariantPlex™ Complete Solid Tumor (430 genes) and VariantPlex™ Pan Solid Tumor (185 genes) are NGS DNA-based panels, which in addition to the detection of somatic variants (SNVs, InDels and CNVs) also allow the determination of tumor mutational burden (TMB) and microsatellite instability (MSI).

These panels could be used separately or in combination with the RNA-based panel FusionPlex™ Pan Solid Tumor v2 (137 genes) to detect gene fusions and exon-skipping mutations. Together, they enable a comprehensive genomic profiling of solid tumors using all relevant biomarkers.

A wide range of NGS kits for the detection of SNVs, InDels and CNVs in somatic and germinal samples.
The advantage of the kits is the use of molecular barcodes (MBCs) and an easy workflow thanks to a unique system of lyophilized reagents.
The Archer® Analysis v7 software with its own ArcherQuiver™ database connected to the Ensembl VEP, Clinvar and COSMIC databases is used to evaluate the results.

The preparation of the libraries is based on the unique patented AMP technology, the main advantages of which are robustness and easy customization of the panels.

AB0144	VariantPlex™ Complete Solid Tumor
AB0142	VariantPlex™ Pan Solid Tumor
AB0137	FusionPlex™ Pan Solid Tumor v2
AB0281	VariantPlex™ Complete Solid Tumor + FusionPlex™ Pan Solid Tumor v2
AB0279	VariantPlex™ Pan Solid Tumor + FusionPlex™ Pan Solid Tumor v2

For more information, please contact us by e-mail: diagnostika@pentagen.cz