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LAMP Human CYP2C9 mutation KIT

Product code: LC-CYP2C9-LP
Producer: LaCAR MDx
Obrazek produktu - LAMP Human CYP2C9 mutation KIT
Test for the detection of 2 alleles of the CYP2C9 gene affecting the metabolism of important drugs using LAMP technology.
Dokumenty ke stažení

Documents to download

CE_LaCAR_CYP2C9-LP_EN.pdf .pdf SDS_LaCAR_KOH_CE_EN.pdf .pdf SDS_LaCAR_LB_LP_EN.pdf .pdf

More detailed product information

LAMP Human CYP2C9 mutation KIT is a genetic diagnostic test enabling the detection of 2 alleles of the CYP2C9 gene that cause CYP2C9 enzyme deficiency:

  • CYP2C9*2: rs1799853;
  • CYP2C9*3: rs1057910

Deficiency of this enzyme affects the metabolism of many important drugs (anticoagulants - Warfarin, anticonvulsants, antihypertensives, etc.), which can lead to insufficient response to treatment or serious side effects.

 

The test is based on robust and sensitive LAMP technology followed by melting curve analysis (TaqMan probes). The main advantage of the products is the simplicity and speed of analysis without the need for DNA isolation. Positive controls are included in the kits.

The products are CE-IVD certified and compatible with most available rtPCR instruments (LightCycler 480, CFX96, CFX Opus, MIC, QuantStudio 1, 3, 5).


For more information, please contact us by e-mail: diagnostika@pentagen.cz