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VariantPlex™ Complete Solid Tumor (430 genes) and VariantPlex™ Pan Solid Tumor (185 genes) are NGS DNA-based panels, which in addition to the detection of somatic variants (SNVs, InDels and CNVs) also allow the determination of tumor mutational burden (TMB) and microsatellite instability (MSI).
The new VariantPlex v2 panels also allow the determination of HRD status. With the original VariantPlex panels, the HRD module can be used as a spike-in if required.
These panels could be used separately or in combination with the RNA-based panel FusionPlex™ Pan Solid Tumor v2 (137 genes) to detect gene fusions and exon-skipping mutations. Together, they enable a comprehensive genomic profiling of solid tumors using all relevant biomarkers.
A wide range of NGS kits for the detection of SNVs, InDels and CNVs in somatic and germinal samples.
The advantage of the kits is the use of molecular barcodes (MBCs) and an easy workflow thanks to a unique system of lyophilized reagents.
The Archer® Analysis v7 software with its own ArcherQuiver™ database connected to the Ensembl VEP, Clinvar and COSMIC databases is used to evaluate the results.
The preparation of the libraries is based on the unique patented AMP technology, the main advantages of which are robustness and easy customization of the panels.
| AB0144 |
VariantPlex™ Complete Solid Tumor |
| AB0142 |
VariantPlex™ Pan Solid Tumor |
| AB0137 |
FusionPlex™ Pan Solid Tumor v2 |
| AB0281 |
VariantPlex™ Complete Solid Tumor + FusionPlex™ Pan Solid Tumor v2 |
| AB0279 |
VariantPlex™ Pan Solid Tumor + FusionPlex™ Pan Solid Tumor v2 |
For more information, please contact us by e-mail: diagnostika@pentagen.cz