The xGen™ Methylation-Sequencing DNA Library Preparation Kit utilizes Adaptase™ technology that efficiently captures bisulfite-converted ssDNA molecules into library molecules for epigenetic research studies (whole genome bisulfite sequencing or targeted Methyl-Seq).
The kit's features:
- Comprehensive sample representation - uniform methylome genome coverage by whole genome bisulfite sequencing (WGBS)
- Low bias library preparation from low input amounts - supports inputs down to single cell
- High multiplex capability - pre-plated UDI primers enable multiplexing of up to 1536 samples
- Compatible with xGen Normalase™ technology - streamlines normalization of libraries enzymatically for a single library pool
- Powered by xGen Adaptase technology - template independent adapter attachment reduces workflow time while generating a less biased library
- Simple, 2-hour workflow for bisulfite-converted samples
- Workflow design for easy automation
The kit includes amplification polymerase, bisulfite conversion module not provided (recommend Zymo), indexing primers also supplied separately.