The xGen Acute Myeloid Leukemia (AML) Cancer Hyb Panel comprises 11,731 xGen Hyb Probes, spanning 1.19 Mb of the human genome, for research using targeted enrichment of 260 AML-associated genes, for more efficient identification of disease-causing mutations in research samples.
The panel is composed of individually synthesized xGen Hyb Probes that have a 5’ biotin group for capture with streptavidin-coated beads.
The xGen Hybridization Capture Core Reagents (xGen Hybridization and Wash Kit, xGen Universal Blockers, xGen Library Amplification Primer Mix, and/or xGen Human Cot DNA) are supplied separately.
NEW! The latest version of xGen™ Hyb and Wash v3 Kit Reagents is now available, offering:
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Reduced minimum DNA input to 100 ng (from 500 ng)
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Shortened hybridization time to 1 hour (from 4 hours)
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Simplified workflow with no need for buffer preheating
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Reduced number of wash steps to 3 washes (from 6 washes)
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Overall preparation time reduced by 10% and hands-on time by 20%
A list of included genes is available upon request.
