info@pentagen.cz
+420 734 151 200
Od 8:00 do 15:30
Čeština English Polski Magyar
  1. Homepage
  2. Product categories
  3. Molecular diagnostics
  4. Oncogenetics
  5. Hereditary tumor syndromes
  6. TarCET Hereditary Cancer Panel

TarCET Hereditary Cancer Panel

Product code: ET211-00-2016
Producer: Medicover Genetics
Detection of SNV, InDel and CNV germline mutations for a hereditary cancer syndromes by NGS.
Dokumenty ke stažení

Documents to download

TarCET KIT IVDR PR28112024 (1).pdf .pdf FSC-TarCET-KIT.pdf .pdf

More detailed product information

NGS panel for detection of germline mutations (SNV, InDel) for diagnosis of various hereditary cancer syndromes, which includes 62 genes.



Library preparation from buccal swabs or blood is based on hybridization capture technology. The solution includes Sirius Genetic Data Management, which can be used for sequencing run planning or maximizing cartridge capacity utilization.

The kit is validated for Illumina NGS sequencers.

VEGA bioinformatics software can be used for data evaluation.


 

List of included genes:

APC, ATM, BAP1, BARD1, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN2A, CHEK2, DDB2, DICER1, EPCAM, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, GREM1, HOXB13, MEN1, MLH1, MRE11, MSH2, MSH6, MUTYH, NBN, PALB2, PMS2, POLD1, POLE, POLH, PTEN, RAD50, RAD51C, RAD51D, RB1, RET, SDHAF2, SDHB, SDHC, SDHD, SLX4, SMAD4, SMARCA4, STK11, TP53, VHL, XPA, XPC

 

 

NEW! Medicover Genetics has obtained their certification under the new In Vitro Diagnostic Regulation (IVDR; 2017/746) for all NGS reagents incl. TarCET IVD kits:

 

TarCET Metabolic Kit  223 genes
TarCET Hereditary Cancer Kit  62 genes
TarCET Carrier Screening Core Kit  19 genes
TarCET Carrier Screening Comprehensive Kit  228 genes
TarCET Neonatal Kit  140 genes
TarCET Aortopathy Kit  48 genes
TarCET Arrhythmia Kit  42 genes
TarCET Cardiomyopathy Kit 98 genes
TarCET Congenital Heart Defects Kit  80 genes
TarCET FH, PH and RAS Kit  11, 11 a 30 genes
TarCET Cardiac Comprehensive Kit  292 genes
TarCET Infertility Kit  Female 54 genes, Male 39 genes

For more information, please contact us by e-mail: diagnostika@pentagen.cz