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Test niPOC

Product code: P2004
Producer: Igenomix
Obrazek produktu - Test niPOC
Advanced non-invasive genetic test

More detailed product information

The niPOC (Non-invasive Product of Conception) test is an advanced non-invasive genetic test that uses a blood sample from the mother to determine whether a miscarriage was caused by a chromosomal abnormality.

 

What does the niPOC test detect?
The test analyzes 24 chromosomes and identifies:

  • Aneuploidy – Changes in the number of chromosomes (e.g., trisomy).

  • Deletions and duplications – Loss or gain of chromosomal fragments.

  • Ploidy alterations – Haploidy, triploidy, tetraploidy.

  • Tissue origin – Determines whether the sample is of fetal or maternal origin through microsatellite STR analysis.

 

 

How is the test used?

  1. Sample collection: A 7–10 ml peripheral blood sample from the mother is collected into a special Streck Tube, which is part of the Igenomix collection kit.
  2. Timing of sample collection: The blood sample should be collected before the fetal tissue evacuation, if possible. If pharmacological treatment is used for evacuation, the blood should be drawn before the administration of the medication.
  3. Sample collection and transport: The sample is sent to the Igenomix laboratory, where it is analyzed using next-generation sequencing (NGS).
  4. Results: Results are usually available within 7–10 working days from receipt of the sample at the laboratory.

 

 

Advantages of the niPOC test

  • Non-invasive: Only a blood sample from the mother is required, eliminating the need for surgical tissue collection.

  • High informativeness: Results of fetal origin are obtained in >85% of cases, significantly higher than traditional methods.

  • Quick results: Results are available in a short time, usually within 7–10 working days.

  • No contamination by maternal cells: The analysis is capable of detecting the presence of maternal cells and excluding their impact on the results.

  • Suitable for early pregnancies: The test is recommended from the 5th week of pregnancy.

 

Who should consider this test?

  • Women after miscarriage: The test is suitable for any woman who has experienced a miscarriage, especially those who have had multiple miscarriages or undergone assisted reproduction.

  • Before planning another pregnancy: It helps identify possible genetic causes of previous miscarriages, which can inform decisions about future pregnancies.


For more information, please contact us by e-mail: reprodukce@pentagen.cz