eazyplex® Gram-negative Set

eazyplex® Gram-negative resistance panels are a series of rapid molecular diagnostic assays designed for the detection of key antibiotic resistance genes in Gram-negative bacteria.

More detailed product information

Resistance in Gram-negative pathogens—especially due to carbapenemases and ESBLs—is a significant clinical challenge. The eazyplex® SuperBug series provides rapid, culture-confirmed detection of these resistance genes. These panels are ready-to-use, lyophilized LAMP assays that do not require DNA extraction, and most deliver results in ~15–20 minutes.

Target Resistance Genes

The eazyplex® SuperBug panels cover a broad range of key resistance targets:

Carbapenemases: NDM, VIM, KPC, OXA-48 group, OXA-181/232
Extended-spectrum β-lactamases (ESBLs): CTX-M-1 group, CTX-M-9 group
Other rare β-lactamases: IMP, IMI, GES, GIM
AmpC β-lactamases and additional markers relevant for Acinetobacter and Enterobacteriaceae species.

Available panel kits include:

SuperBug CRE (E7600) – Focused on major carbapenemases and ESBLs
SuperBug complete (A E7601; B E7602; C E7608) – Extended OXA and ESBL coverage
SuperBug expert (E7609) – Expanded panel including rarer carbapenemases
SuperBug Acineto (E7607) – Targeting resistance genes in Acinetobacter species
SuperBug AmpC (E7606) – AmpC β-lactamase detection
SuperBug basic (E7603) – Core resistance gene panel.

How It Works

Uses LAMP (Loop-Mediated Isothermal Amplification) for fast, specific resistance gene detection
Direct testing from cultured isolates or positive blood cultures — no DNA extraction needed
Lyophilized reagents stable and ready to use
Results in ~15–20 minutes, depending on the panel.

Key Benefits

Rapid genetic resistance profiling supports early clinical decisions
Broad coverage of essential Gram-negative resistance mechanisms
Simple and streamlined workflow
Flexible panel choices tailored to laboratory and clinical needs.

Intended Use

These panels are designed for clinical microbiology laboratories and hospital diagnostic settings as an aid in rapid detection of antibiotic resistance genes in Gram-negative bacteria—critical for:

Optimizing antimicrobial therapy
Infection prevention and control
Faster turnaround compared with culture-based resistance testing

Quick resistance gene identification enables clinicians to adjust treatments sooner and supports better outcomes in serious infections.

Full product details can be found here: https://www.eazyplex.com/resistenzen-bei-gram-negativen

For more information, please contact us by e-mail: diagnostika@pentagen.cz