SALSA digitalMLPA Hereditary Cancer Panel 1

Product code: D001, DRK01-IL, BP01-IL
Producer: MRC HOLLAND B.V
Obrazek produktu - SALSA digitalMLPA Hereditary Cancer Panel 1
Reliable and effective CNV analysis of 28 genes using unique digitalMLPA technology

More detailed product information

Digital MLPA is a patented technology of MRC Holland that combines the advantages of classic MLPA methodology and Next-generation sequencing.
Enables reliable and efficient CNV analysis through 1000 probes.

The evaluation of the results is made possible by the unique Coffalyser digitalMLPA software

Principle of the method: https://support.mrcholland.com/kb/articles/video-what-is-digitalmlpa 



SALSA digitalMLPA probemix D001-D1 Hereditary Cancer Panel 1 allows detection of CNVs in genes associated with hereditary predisposition to breast, ovarian, colorectal, gastric, prostate, pancreatic or endometrial cancer, or melanoma.

The panel consists of 723 probes, including 575 probes for 28 genes associated with hereditary cancer syndromes.

The kit is compatible with Illumina's sequencers and is intended for research use only (RUO).

 

List of genes included: MUTYH, EPCAM, MSH2, MSH6, BARD1, MLH1, BAP1, MITF, APC, PMS2, NBN, CDKN2A, BMPR1A, PTEN, ATM, CDK4, POLE, BRCA1, BRCA2, SCG5/GREM1, PALB2, CDH1, TP53, RAD51D, RAD51C, BRIP1, SMAD4, STK11, CHEK2

 

Actual product information and documents can be found on the MRC Holland website.


For more information, please contact us by e-mail: diagnostika@pentagen.cz